Physical and chemical properties: Ring-ethyl ester is a pyrimidine herbicide, its structure and pyrimidine hydroxy acid similar. Pure ethyl ester ring appearance of a white odorless crystalline powder; melting point: 163 ℃; starting powder at 300 ℃, vapor pressure (25 ℃): 2.2 × 10-8Pa; water solubility (25 ℃): 1.8mg / L; octanol / water partition coefficient (25 ℃): LogPow = 2.6;
Chemical Name: CAS: 7 - [(4,6 - dimethyl -2-pyrimidinyl) thio] -3 - methyl -1 (3H) - isopropyl and furanone; IUPAC: (RS) -7 - (4 , 6 - dimethoxy-pyrimidine -2 - based thio) -3 - methyl -2 - benzofuranyl -1 (3H) - one C15H14N2O4S Molecular Weight: 318.40
Central TC-ethyl ester ≥ 96, the appearance of light brown fine powder; PH value: 6.9; organic solvents Solubility (25 ℃): dichloromethane 99g / L, acetone, 14g / L, ethyl acetate 6.1 g / L, toluene 4.0g / L, methanol, 1.4g / L, octanol-400mg / L, hexane 30mg / L;; in thermal and air stability. Ring-ethyl ester 250 g / l SC appearance is white to pale yellow liquid. PH value of 5 ~ 9; suspension rate: ≥ 70; mobility: the dumping of residues of up to 8, the largest 1% of the rinse residue; cold, heat and room temperature storage stability.
Toxicity: Central, TC-ethyl ester in rat acute oral LD50> 5000mg/kg, acute dermal LD50> 2000mg/kg, acute inhalation LC50> 5540mg/m3; rabbit skin, eye irritation; guinea pig skin allergy ( allergenicity) test result is non-allergenic; rat subchronic feeding toxicity test 90d maximal no-effect dose: male rats were 23.8mg/kg • d, female rats were used as 25.5mg/kg • d. 4 mutagenicity tests: Ames test, mouse bone marrow micronucleus test in vivo UDS test in vitro mammalian cell chromosome aberration test were negative, no mutagenic effect.
Ring-ethyl ester 250 g / l SC rat acute oral LD50> 3000mg/kg, acute dermal LD50> 4000mg/kg, acute inhalation LC50> 1657mg/m3; rabbit skin, the eyes are irritating; guinea pig skin allergic reaction (allergenicity) test results are moderately allergenic. Central TC-ethyl ester and 250 g / l SC are low-toxicity herbicide.
Environmental Biotechnology Safety Assessment: Central, TC-ethyl ester of carp LC50 (96h)> 100mg / L; quail LD50> 2000mg/kg; Bee oral LD50 (48h)> 138μg / bee, contact LD50 (48h)> 100μg / bees; family leaves eaten poisoned France, (96h) LC50> 1250mg/kg. 250 g / l suspension of the rainbow trout LC50 (96h) for the 76mg / L, bees oral and contact LD50 (48h)> 100μg.ai / bee, home encroaching poison leaves France, (96h) LC50 5000mg/kg. Central TC-ethyl ester and 250 g / l SC pairs of fish, birds, bees, silkworm are low toxicity.