5,8,11 - eicosatriynoic acid
ETI is a leukotriene antagonist and selective 5 - LO (5 - lipoxygenase) inhibitor
Cas: 13488 - 22 - 7
HClFormula Weight: 300.44
ETI, 5,8,11 - eicosatriynoic acid, demonstrates the ability to inhibit 5 - LO (5 - lipoxygenase) activity and halt biosynthesis of leukotriene C4 by mastocytoma cells. Studies suggest that ETI also reduces oxidative metabolism of arachidonic acid (sc - 200770). ETI also displays anti - proliferative properties which result from 5 - LO selective inhibition and cause a decrease in platelet - induced growth of fibroblast cells. ETI is an inhibitor of 12 - LO, 15 - LO and GST.